Akili’s team describes its philosophy on its website as “establishing a new era in cognitive medicine.” The company writes:[believes] Effective medicine can also be fun and engaging [by] Creating a new class of digital medicines for people living with cognitive impairments, delivered through an engaging video game experience. ” On the company’s leadership page, Akili states that the employee, known colloquially as Akillian, is “committed to challenging the medical status quo to help people living with cognitive impairments,” and the company says that “We are passionate about connecting top-notch science and entertainment with great users,” he added, an experience that will forever change the way medicines are designed and delivered. ”
Akili’s flagship product is EndeavorRx, which the company says is “the first treatment of its kind for children with ADHD delivered through an action video game experience.” EndeavorRx is built on proprietary technology developed in-house by Akili, and its products are[improves] Attentional function measured by a computer-based test in children 8 to 12 years of age with evidence of attention problems, primarily inattentive or combined ADHD. ”
Building on EndeavorRx’s underlying Selective Stimulus Management Engine Technology (SSME), Akili released EndeavorOTC in September. The app, available on iOS and Android, is billed as a video game app “clinically designed to treat and improve adult girlfriend ADHD symptoms anytime, anywhere.” The app’s website states that in clinical studies conducted with EndeavorOTC, nearly three-quarters, or 73%, of participants reported seeing an improvement in their quality of life using the software. got it. Among the research highlights, the site found that 53% of people can better manage multiple tasks at once, 54% can better keep track of everyday items like keys and wallets, and 60% He says the project can be completed in less time. in a timely manner.
SSME has been validated in more than a dozen clinical trials for conditions that affect cognition. These include depression, multiple sclerosis, autism spectrum disorder, and even long coronavirus.
“EndeavorOTC is a digital therapy specifically designed to improve attentional control,” Dr. Scott Collins, Akili’s chief medical officer, recently told me in an email interview. . “It comes in the form of an immersive mobile video game that is clinically proven to improve attention and concentration, especially in adults with ADHD.” It’s built on the same technology as Akili’s EndeavorRx, the first and only FDA-cleared video game for treatment.”
Our conversation coincided with ADHD Awareness Month in October.
Dr. Collins himself is a licensed clinical psychologist and spent more than 20 years on the faculty of the Duke University School of Medicine’s Department of Psychiatry and Behavioral Sciences, and says that research has shown that video games are highly effective in treating dementia. “It has been done,” he explained. Conditions involving carelessness. EndeavorOTC’ only when the software is carefully designed by clinicians and neuroscientists as a medical treatment. He said EndeavorOTC is intentionally designed to “target and stimulate the parts of the brain that control cognitive functions such as attention.” Dr. Collins added that when someone plays a game, they are asked to complete a specific task while eliminating distractions. Its cumulative effect is to train the brain to generalize this behavior in real life. He said the game adapts to the player’s abilities in real time, optimizing the challenge and keeping players interested and focused.
“We developed the game because [and] After rigorously testing it in a study of more than 200 adults with ADHD, the FDA recognized an urgent need to introduce new non-drug treatments for ADHD, so it was approved under FDA enforcement discretion. I made it available. The current standard of treatment is medication, which works for many people but not everyone,” Dr. Collins said. “Many people are suffering from side effects, cannot mix it with other drugs, or have a hard time getting the drug given the ongoing stimulant shortage, lack of mental health professionals and Together, we realized there was a huge gap between the care needed and the treatments available. Patients simply needed more options.”
He added: “Completing tasks at the same time while eliminating distractions increases therapeutic efficacy. [EndeavorOTC] Targets areas of the brain responsible for cognitive functions such as concentration, improving attention and daily life functions. The algorithm adapts to each user in real time, providing a personalized experience and challenging the user at an optimized level to improve targeted cognitive functions. ”
When asked about societal perceptions of ADHD, Dr. Collins said that ADHD is a disorder that is less understood in adults than in children. He described adult ADHD as an epidemic, noting that 1.1 million people in the United States have ADHD, but it often goes undiagnosed and untreated. Dr. Collins said there are signs that diagnosis and disability rates have increased in recent years, especially coinciding with the pandemic. Living with undiagnosed ADHD can have a “devastating impact on many aspects of life,” including career, interpersonal relationships and mental health, he said. Additionally, Dr. Collins said major changes are occurring with a “surge in adults” seeking care for ADHD symptoms. As always, there is still work to be done.
The arrival of EndeavorOTC is notable because, as Dr. Collins told me, ADHD treatment hasn’t changed much since the 1970s. Drug administration has not changed and patient outcomes have not changed. In other words, tools like EndeavorOTC “have the potential to change many lives.” Dr. Collins said he is “excited for the opportunity to spread awareness and help patients think innovatively about how they manage their care,” and that the opportunity for education and awareness is what he calls “really passionate about evangelism.” He added that “there are”
Feedback on EndeavorOTC is positive. Dr. Collins said many patients feel that EndeavorOTC has helped them regain control of their lives on both a personal and professional level. He said the feedback was “particularly acute” against the backdrop of ongoing stimulant shortages and challenges in accessing treatment. Dr. Collins said many adults struggle with symptoms of ADHD and are “relieved” to discover alternative treatments like Endeavor OTC, which can be used alone or in combination with medications and other medications.
Additionally, Dr. Collins cited numerous statistics from Akiri’s research, including the numbers mentioned earlier in this article. Of the numbers, he said, the results of clinical studies “speak for themselves.”
More detailed information about the results is available online.
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